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Meiotic Nondisjunction & Aneuploidy Simulator (2D)

A 2D top-down diagram of meiosis I and II: dial in nondisjunction probability at each division, drag to pan and scroll to zoom, and watch trisomy and monosomy gametes form.

Genetics & Evolution2DModerate60 FPS📱 Mobile-adapted⇄ 3D version
2d-genetics-biology ↗ Open standalone

Two homologous chromosome pairs are carried through a full meiosis — prophase condensation, metaphase I alignment, anaphase I homolog separation, cytokinesis, metaphase II alignment and anaphase II sister-chromatid separation — ending in four haploid gametes, drawn as a flat top-down diagram you can pan and zoom. Independent nondisjunction probabilities for meiosis I and meiosis II let you push the system toward producing trisomic (n+1) and monosomic (n−1) gametes on demand, while live readouts report each trial's exact chromosome count per gamete and the running aneuploidy rate across every trial you've run — the same formula as the 3D version, P(aneuploid) = p1 + (1 − p1)·p2, made visible one trial at a time.

⚙ Under the hood

A 2D top-down diagram of meiosis I and II: dial in nondisjunction probability at each division, drag to pan and scroll to zoom, and watch trisomy and monosomy gametes form from the same p1 + (1-p1)*p2 formula as the 3D version.

geneticsmeiosisnondisjunctionaneuploidychromosomesbiology2d-canvas

2D · HTML5 Canvas 2D · 60 FPS target · runs fully client-side, no install

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