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Transition-Metal Cross-Coupling Catalysis

Interactive 3D simulation of an organometallic catalytic cycle: watch a palladium center run oxidative addition, transmetalation (or migratory insertion) and reductive elimination for Suzuki, Heck and Negishi cross-couplings, with ligand bulk, catalyst loading and temperature controlling turnover.

Chemistry & Materials3DAdvanced60 FPS

Organometallic chemistry lives at the meeting point of carbon and metal: a metal-carbon bond, once formed, opens reactivity that neither piece has alone. This simulation visualizes the catalytic cycle at the heart of Suzuki, Negishi and Heck cross-coupling — the reactions that build most of the carbon-carbon bonds in modern pharmaceuticals and agrochemicals. Watch palladium centres cycle through oxidative addition, transmetalation (or migratory insertion for Heck) and reductive elimination, and see how catalyst loading, ligand bulk and temperature change how fast the reaction turns substrate into product.

⚙ Under the hood

Watch parallel palladium catalytic sites cycle through oxidative addition, transmetalation (or migratory insertion for Heck) and reductive elimination for Suzuki, Negishi and Heck cross-coupling, with catalyst loading, ligand bulk and temperature controlling turnover number and frequency in real time.

Three.jsorganometallic chemistrycatalysiscross-couplingpalladium

3D · Three.js / WebGL renderer · 60 FPS target · runs fully client-side, no install