🧠 Manic Episode Treatment Simulator

Acute Mania — Elevated YMRS at Baseline

Placeholder: patient presents with severe manic symptoms and high YMRS.

• ~32: Baseline YMRS (Placeholder severe range)
• ↓↓: Sleep need (Placeholder short sentence)
• High: Racing thoughts (Placeholder short sentence)
• Low: Insight (Placeholder short sentence)

Recognizing the acute manic episode

Placeholder: elevated mood, pressured speech, and grandiosity dominate presentation.

Choosing an Antipsychotic Agent

Placeholder: three agents differ in sedation and speed of action.

• Sedating: Quetiapine (Placeholder short sentence)
• Fast-acting: Olanzapine (Placeholder short sentence)
• Activating: Aripiprazole (Placeholder short sentence)
• Tolerability: Choice driver (Placeholder short sentence)

Agent trade-offs in acute mania

Placeholder: sedation, metabolic risk, and speed guide agent choice.

Dose Titration — Days 1 Through 3

Placeholder: dose is escalated stepwise over the first days.

• 3 days: Titration span (Placeholder short sentence)
• Expected: Sedation rise (Placeholder short sentence)
• Vitals, EPS: Monitoring (Placeholder short sentence)
• Target dose: Goal (Placeholder short sentence)

Stepwise dose escalation

Placeholder: rapid but cautious titration reduces early dropout.

Symptom Response — Days 4 Through 7

Placeholder: agitation and racing thoughts begin to settle.

• Visible: YMRS drop (Placeholder short sentence)
• Improving: Sleep return (Placeholder short sentence)
• ≥50% drop: Response def. (Placeholder short sentence)
• Monitored: Side effects (Placeholder short sentence)

Tracking early clinical response

Placeholder: symptom trajectory guides continued dosing decisions.

YMRS Remission Assessment

Placeholder: remission defined as YMRS score of 12 or below.

• YMRS ≤12: Remission cut (Placeholder short sentence)
• ~2 weeks: Timeframe (Placeholder short sentence)
• Continue dose: Maintenance (Placeholder short sentence)
• Ongoing: Relapse watch (Placeholder short sentence)

Defining and confirming remission

Placeholder: sustained low YMRS confirms treatment success.

Placeholder: remission is confirmed by sustained YMRS ≤12 over time.