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Myostatin Signaling 2D: Fiber Field & Dose-Response

2D-native companion to the myostatin (GDF-8) / ActRIIB / SMAD2-3 signaling simulator: a native 2D hex-packed myofiber cross-section grid plus a live Hill-function dose-response plot and mass-vs-time strip chart, driven by the same signaling arithmetic.

Biophysics2DModerate60 FPS📱 Mobile-adapted⇄ 3D version

Muscle mass is set by a molecular tug-of-war: myostatin (GDF-8) signaling through ActRIIB and SMAD2/3 restrains growth, while resistance-training signaling through IGF-1/Akt/mTORC1 drives it. This 2D companion renders that balance two ways at once — a native hex-packed field of myofiber cross-sections that thickens or thins fiber-by-fiber, and a full Hill-function dose-response plot with a live mass-vs-time strip chart — the same signaling arithmetic behind myostatin-knockout "double-muscling" cattle and the anti-myostatin biologics now in trials for muscular dystrophy and sarcopenia, laid out as plain 2D curves and grids instead of a 3D bundle.

⚙ Under the hood

2D-native companion to the myostatin (GDF-8) / ActRIIB / SMAD2-3 signaling simulator: a hex-packed 2D myofiber cross-section field that grows or shrinks fiber-by-fiber, paired with a live Hill-function dose-response plot and a mass-vs-time strip chart, driven by the same signaling arithmetic as the 3D model.

myostatinmuscle growthSMAD signalingmTORC1hypertrophybiophysicsdose-response2D simulation

2D · HTML5 Canvas 2D · 60 FPS target · runs fully client-side, no install