HomeBiomaterial Scaffold Design for Tissue EngineeringContact Guidance Order Parameter: Top-Down Cell Alignment on Micro-Grooves

Contact Guidance Order Parameter: Top-Down Cell Alignment on Micro-Grooves

Interactive 2D top-down simulator of contact guidance: watch a cell population migrate on a micro-grooved biomaterial surface and align to the groove direction, with a live rose-plot of headings, a groove cross-section panel and a nematic order-parameter readout.

Biomaterial Scaffold Design for Tissue Engineering2DModerate60 FPS📱 Mobile-adapted⇄ 3D version
2d-biotech-topic-34 ↗ Open standalone

This 2D companion renders the same contact-guidance mechanism as its 3D sibling — a nematic alignment torque that turns migrating cells toward a micro-grooved biomaterial surface's ridge direction — from directly above, so the population's collective ordering reads at a glance. A live rose diagram in the corner turns each cell's heading into a two-lobed polar histogram that visibly sharpens as the population aligns, a groove cross-section panel ties the depth and pitch sliders straight to the physical bump profile they control, and the four readouts (order parameter, guidance strength, migration anisotropy, elapsed simulated time) update in real time. Drag the main view to pan across the periodic surface and scroll to zoom in on individual cells turning to track the ridges.

⚙ Under the hood

2D top-down simulator of contact guidance: watch a cell population migrate on a micro-grooved biomaterial surface and align to the groove direction, with a live two-lobed rose plot of headings, a groove cross-section panel and a nematic order-parameter readout, as you tune groove depth, groove pitch, cell motility and population size.

biomaterialstissue engineeringcontact guidancecell alignmentsurface topographyimplant surfaceorder parameterrose plot

2D · HTML5 Canvas 2D · 60 FPS target · runs fully client-side, no install

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