DNA Replication Fork
Interactive 3D simulation of a DNA replication fork: helicase unwinds the double helix, DNA polymerase synthesizes the leading strand continuously and the lagging strand in Okazaki fragments, and ligase seals the gaps.
DNA replicates semiconservatively: the double helix unwinds and each old strand serves as a template for a new complementary partner. Because DNA polymerase only synthesizes 5'→3' and the two template strands are antiparallel, one new strand (leading) is built in one continuous pass right behind helicase, while the other (lagging) can only be built backwards in short Okazaki fragments that DNA ligase later stitches together. This simulation renders that fork in real time — unwinding, both synthesis modes, and proofreading — so you can see exactly why replication needs a whole enzyme toolkit rather than a single copier.
Interactive 3D simulation of a DNA replication fork: helicase unwinds the double helix while DNA polymerase builds the leading strand continuously and the lagging strand as Okazaki fragments that ligase seals, with adjustable fork speed and proofreading fidelity.
3D · Three.js / WebGL renderer · 60 FPS target · runs fully client-side, no install