Home▸Bariatric Surgery vs Pharmacotherapy▸Sleeve Gastrectomy vs GLP-1 Therapy Comparator

🏥 Sleeve Gastrectomy vs GLP-1 Therapy Comparator

This simulation compares the effectiveness of sleeve gastrectomy and GLP-1 therapy in managing obesity. It evaluates various factors such as weight loss, metabolic improvements, and long-term outcomes for patients.

Bariatric Surgery vs Pharmacotherapy2DModerate60 FPS

Two Roads From the Same Starting Point

Placeholder: obesity baseline, both options open.

≥35: Eligible BMI (surgery) (or ≥30 with comorbidity)
≥27: Eligible BMI (GLP-1) (with comorbidity)
~42%: US adults w/ obesity (placeholder prevalence figure)
3: Decision drivers (efficacy, durability, risk)

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Mechanical Restriction vs Pharmacologic Suppression

Placeholder: two mechanisms diverge from day one.

~80%: Stomach removed (sleeve) (greater curvature resected)
Hypothalamus: GLP-1 receptor target (+ gut, vagal afferents)
Immediate: Surgery onset (anatomic, permanent)
Gradual: Drug onset (weekly dose titration)

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Diverging Curves Across the First Year

Placeholder: surgery front-loads loss, drug is steadier.

~25%: Surgery %TWL @ 12mo (placeholder curve estimate)
~15%: GLP-1 %TWL @ 12mo (placeholder curve estimate)
~12–18mo: Surgery plateau (placeholder timing)
~12–24mo: GLP-1 plateau (placeholder timing)

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What Happens When Treatment Stops

Placeholder: anatomy persists, drug effect can reverse.

~85%: Surgery durability (weight kept, placeholder)
~20%: GLP-1 durability off-drug (weight kept, placeholder)
Fast: Regain after stopping GLP-1 (placeholder timeframe)
Low: Reoperation rate (sleeve) (placeholder figure)

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Risk, Cost, and Adherence Side-by-Side

Placeholder: final tradeoff summary across both paths.

6.1/10: Surgical risk score (placeholder composite)
3.4/10: GLP-1 risk score (placeholder composite)
~$27k: Surgery 5-yr cost (placeholder estimate)
~$68k: GLP-1 5-yr cost (placeholder estimate)

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⚙ Under the hood

This simulation compares the effectiveness of sleeve gastrectomy and GLP-1 therapy in managing obesity. It evaluates various factors such as weight loss, metabolic improvements, and long-term outcomes for patients.

CanvasBiomedicine

2D · HTML5 Canvas 2D · 60 FPS target · runs fully client-side, no install