Home▸Trauma Center Resuscitation Protocol▸3D TBI & ICP Management: Monro-Kellie Doctrine

🧠 3D TBI & ICP Management: Monro-Kellie Doctrine

Grow a mass lesion inside a real 3D cranial vault and drive tiered Brain Trauma Foundation therapy — the same Monro-Kellie pressure-volume model as the 2D version, now walked around in genuine 3D space with orbit controls.

Trauma Center Resuscitation Protocol3DAdvanced60 FPS📱 Mobile-adapted⇄ 2D version
3d-tbi-intracranial-pressure-management ↗ Open standalone

How the 3D Monro-Kellie ICP model works

Grow a mass lesion inside a real 3D cranial vault and drive tiered Brain Trauma Foundation therapy — the same Monro-Kellie pressure-volume model as the 2D version, now walked around in genuine 3D space with orbit controls.

The control panel exposes seven verified parameters — hematoma volume, MAP, sedation depth, PaCO₂ target, head-of-bed elevation, EVD drainage, hyperosmolar therapy choice and decompressive craniectomy — each wired directly into the same capacity and ICP equations as the 2D canvas version. The live readout panel reports ICP, CPP, PaCO₂, mass lesion volume, compensatory reserve and elapsed simulation time, all recomputed every frame from the same physiology state the vault renders.

⚙ Under the hood

Every frame computes a compensatory capacity in mL — baseline CSF/venous displacement room, plus head-of-bed elevation, EVD drainage, sedation-driven CMRO₂ reduction, PaCO₂-driven vasoconstriction, hyperosmolar therapy and (if open) a large craniectomy bonus — then applies the exact exponential pressure-volume relation ICP = 9 + 3.1·(e^(k·excess) − 1), where excess is the lesion volume beyond capacity and k flattens sharply once the vault is decompressed. CPP is simply MAP − ICP. In 3D, the lateral ventricles and basal cistern shrink as compensatory reserve is consumed, the venous sinus ring thins, the hematoma grows as a pulsing red mass that shifts the whole brain mesh off-center (a visible midline shift), and toggling decompressive craniectomy detaches a bone-flap mesh from the skull sphere and reveals a bulging dura through the defect — the same physiology as the 2D canvas, in orbit-able 3D space with a floating 3D pressure dial reading ICP directly off its needle position.

Monro-KellieICPNeurocritical Care

3D · Three.js / WebGL renderer · 60 FPS target · runs fully client-side, no install

What did you find?

Add reproduction steps (optional)