🦠 Trichomoniasis Diagnosis & Metronidazole Treatment Simulator

Wet Mount Microscopy for Trichomonas vaginalis

Saline wet mount shows motile flagellated organisms under the microscope.

• 51-65%: Sensitivity (Placeholder reference value)
• <10 min: Read time (Placeholder reference value)
• ~20 min: Motility window (Placeholder reference value)
• Low: Cost tier (Placeholder reference value)

Microscopic identification basics

Placeholder: motile organism identified by flagella and jerky movement.

NAAT Confirmation of Trichomoniasis

Nucleic acid amplification testing confirms cases missed by microscopy.

• >95%: Sensitivity (Placeholder reference value)
• >95%: Specificity (Placeholder reference value)
• ~1-2 days: Turnaround (Placeholder reference value)
• Swab/urine: Sample type (Placeholder reference value)

Why NAAT outperforms wet mount

Placeholder: amplification detects low organism burden missed on slide.

Single-Dose Metronidazole Treatment

A single 2g oral dose disrupts parasite DNA rapidly.

• 2g PO: Standard dose (Placeholder reference value)
• ~84%: Cure rate (Placeholder reference value)
• High: Adherence (Placeholder reference value)
• Hours: Onset (Placeholder reference value)

Mechanism of single-dose therapy

Placeholder: reduced nitro group forms radicals that damage parasite DNA.

Seven-Day Metronidazole Course

A week-long lower dose course improves clearance in some cases.

• 500mg BID: Standard dose (Placeholder reference value)
• ~92%: Cure rate (Placeholder reference value)
• 7 days: Duration (Placeholder reference value)
• Moderate: Adherence (Placeholder reference value)

When the longer course is preferred

Placeholder: sustained exposure helps overcome partial resistance.

Nitroimidazole Resistance Considerations

Rising resistance markers signal need for retesting and dose changes.

• 4-10%: Resistance rate (Placeholder reference value)
• ~3 months: Retest window (Placeholder reference value)
• Tinidazole: Alt agent (Placeholder reference value)
• 2g x7d: High-dose option (Placeholder reference value)

Managing suspected treatment failure

Placeholder: escalate dose, switch agent, or confirm reinfection.

Placeholder: persistent symptoms after treatment warrant resistance testing.