🌹 Rosacea Vascular Hyperreactivity Simulator

Baseline Facial Vessel Tone

Placeholder: superficial facial vessels sit at normal resting diameter.

• Normal: Resting vessel tone (placeholder metric)
• Steady: Baseline flow (placeholder metric)
• Quiet: Nerve signal (placeholder metric)
• Even tone: Skin appearance (placeholder metric)

Normal vascular tone

Placeholder: healthy vessels constrict and relax within a narrow, stable range.

Neurovascular Dysregulation Mechanism

Placeholder: sensory nerve and vessel signaling loop becomes miscalibrated.

• Elevated: TRPV/TRPA activity (placeholder metric)
• Increased: Neuropeptide release (placeholder metric)
• Amplified: Vessel responsiveness (placeholder metric)
• Lowered: Threshold to trigger (placeholder metric)

Signal miscalibration

Placeholder: sensory nerve fibers over-signal to nearby dermal vessels.

Trigger-Induced Vasodilation Response

Placeholder: heat, spice, or stress rapidly widens facial vessels.

• Seconds: Response latency (placeholder metric)
• High: Dilation magnitude (placeholder metric)
• Heat, spice, stress: Common triggers (placeholder metric)
• Flushing: Visible sign (placeholder metric)

Acute overshoot

Placeholder: the vasodilation response overshoots normal proportional limits.

Persistent Erythema / Flushing Pattern

Placeholder: redness fails to fully resolve between trigger episodes.

• Prolonged: Recovery time (placeholder metric)
• Reddened: Baseline shift (placeholder metric)
• Increasing: Episode frequency (placeholder metric)
• Compromised: Skin barrier (placeholder metric)

Incomplete resolution

Placeholder: vessels stay partly dilated between successive triggers.

Chronic Vessel Dilation (Telangiectasia)

Placeholder: repeated dilation cycles leave vessels permanently widened.

• Fixed dilation: Vessel state (placeholder metric)
• Persistent: Visibility (placeholder metric)
• Low: Reversibility (placeholder metric)
• Laser therapy: Typical treatment (placeholder metric)

Structural vessel change

Placeholder: vessel walls remodel into visibly dilated, fixed telangiectasia.

Placeholder key insight: chronic hyperreactivity can leave lasting vascular marks.