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🩹 Guttate vs Plaque Psoriasis Trigger Simulator

An interactive model of the development of guttate psoriasis following streptococcal throat infection versus chronic plaque type, with different patterns of progression.

Psoriasis & Biologic Therapy2DModerate60 FPS
guttate-plaque-psoriasis-trigger-simulator ↗ Open standalone

Streptococcal Infection as a Psoriasis Trigger

Placeholder: throat strep can kick off an immune cascade toward skin.

  • Strep pharyngitis: Common preceding infection (Placeholder note)
  • 1–3 weeks: Typical latency (Placeholder note)
  • Children/young adults: Age skew (Placeholder note)
  • Molecular mimicry: Mechanism class (Placeholder note)

Immune cross-reactivity basics

Placeholder: streptococcal M-protein resembles skin keratin epitopes.

Placeholder callout: strep throat history matters in new guttate cases.

Guttate Teardrop Lesion Eruption

Placeholder: small drop-shaped lesions appear suddenly and widely.

  • 2–10 mm: Lesion size (Placeholder note)
  • Trunk, limbs: Distribution (Placeholder note)
  • Days: Onset speed (Placeholder note)
  • Teardrop papules: Shape (Placeholder note)

Acute eruption pattern

Placeholder: lesions scatter widely, unlike localized plaques.

Placeholder callout: sudden widespread onset is a hallmark clue.

Chronic Plaque Psoriasis Baseline Pattern

Placeholder: thick scaly plaques settle into fixed body sites.

  • >1 cm plaques: Lesion size (Placeholder note)
  • Elbows, knees, scalp: Distribution (Placeholder note)
  • Weeks to months: Onset speed (Placeholder note)
  • Thick demarcated patches: Shape (Placeholder note)

Chronic baseline features

Placeholder: plaques persist with thick silvery scale over time.

Placeholder callout: chronic plaque type dominates adult psoriasis.

Course Comparison — Resolving vs Chronic

Placeholder: guttate often self-resolves; plaque type usually persists.

  • Weeks–months: Guttate resolution (Placeholder note)
  • Years: Plaque persistence (Placeholder note)
  • Guttate→plaque possible: Conversion risk (Placeholder note)
  • Varies by type: Relapse pattern (Placeholder note)

Divergent trajectories

Placeholder: course pattern guides monitoring and expectations.

Placeholder callout: some guttate cases evolve into chronic plaque disease.

Type-Specific Treatment Approach

Placeholder: therapy choice tracks lesion type and disease course.

  • Topicals, phototherapy: Guttate first-line (Placeholder note)
  • Topicals, biologics: Plaque first-line (Placeholder note)
  • Antibiotics if active: Strep management (Placeholder note)
  • Extent-dependent: Systemic threshold (Placeholder note)

Matching therapy to pattern

Placeholder: treatment intensity scales with chronicity and body surface area.

Placeholder callout: type-specific plans improve outcomes.
⚙ Under the hood

An interactive model of the development of guttate psoriasis following streptococcal throat infection versus chronic plaque type, with different patterns of progression.

CanvasBiomedicine

2D · HTML5 Canvas 2D · 60 FPS target · runs fully client-side, no install

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