Home▸Pharmacogenomics CYP Metabolizer Simulator▸HLA-B*5701 Abacavir Screen in 3D - Pharmacogenomic Test Walkthrough

🧬 HLA-B*5701 Abacavir Screen in 3D - Pharmacogenomic Test Walkthrough

3D companion to the HLA-B*5701 abacavir hypersensitivity screen: a 3D DNA double helix, a curved PCR-SSO probe array, the HLA groove with a draggable abacavir molecule and a swarm of CD8+ T cells, and a screened patient cohort splitting into prescribing branches. Probe sensitivity, cross-reactivity, concordance rule and prevalence drive sensitivity, predictive value and number needed to test.

Pharmacogenomics CYP Metabolizer Simulator3DModerate60 FPS📱 Mobile-adapted⇄ 2D version

Details

CategoryPharmacogenomics CYP Metabolizer Simulator

RenderingThree.js · WebGL

DifficultyModerate

Target FPS60

ControlsDrag to orbit, scroll to zoom; hover and click base pairs, probes and T cells; drag abacavir into the F-pocket; sliders for genotype, prevalence, probe sensitivity, cross-reactivity, required concordant probes and speed; stage navigation, scenario presets, Pause, Step and Reset, with live probe-hit, call, confidence, CD8+ activation, sensitivity and NNT readouts and a hit-distribution graph.

pharmacogenomicsHLA-B*5701abacavirgenotypingwebgl3d-simulation

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⚙ Under the hood

pharmacogenomicsHLA-B*5701abacavirgenotypingwebgl3d-simulation

3D · Three.js / WebGL renderer · 60 FPS target · runs fully client-side, no install