💉 Pediatric Plasma Concentration & Tenfold Error (2D)

The 3D-tagged original walks a pediatric case stage by stage, calculating each drug's dose and draw-up volume from the patient's weight and age. This 2D companion asks a different question: once that dose is in the bloodstream, what does its concentration actually do over time? A one-compartment pharmacokinetic model — the same textbook approximation anesthesiologists use to reason about onset and duration — turns the static dose calculation into a live curve: concentration jumps to a peak at the moment of the IV bolus, then decays exponentially as the drug redistributes and clears, with the decay rate set by each drug's half-life and the peak height set by dose divided by volume of distribution. Switching between propofol, fentanyl, rocuronium and succinylcholine swaps in each drug's real relative dosing, distribution volume and half-life, and switching the age slider through neonate, infant and child bands shows why the youngest patients need the most cautious titration: immature clearance stretches every curve out, keeping the drug in the body — and in the danger zone if a tenfold error is active — for far longer.