Remote Drug Loading — Ammonium-Sulfate Liposome Gradient (2D)

This 2D cross-section simulator draws a single liposome as a disk: a lipid-bilayer ring holding a concentrated ammonium-sulfate interior, bathed in an external buffer carrying a weakly basic drug. Neutral drug molecules diffuse across the membrane; as escaping NH₃ acidifies the interior, crossed molecules protonate and become trapped, building up as a dense core at the centre. Adjust the ammonium load, drug dose and temperature and watch the loading-efficiency readout plateau exactly where the chemistry says it should — the same remote-loading mechanism used to manufacture liposomal doxorubicin and similar clinical nanomedicines, here rendered as a pannable, zoomable flat diagram instead of a 3D scene.