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RNA Interference: RISC Silencing Pathway

Interactive 2D schematic of RNA interference: Dicer processes precursor RNA into siRNA/miRNA duplexes, RISC loads the guide strand and scans mRNA, cleaving or repressing targets by complementarity.

Molecular Biology2DEasy60 FPS📱 Mobile-adapted⇄ 3D version

This simulator draws the RNA interference pathway as a flat schematic: precursor RNA enters from the left, gets diced into small duplexes, loads into RISC, and RISC-guided complexes drift right to scan a pool of mRNA molecules. Depending on how well the guide strand matches each target, the mRNA is either cleaved outright or its translation is silently repressed. Adjust guide–target complementarity, Dicer processing rate and RISC loading rate, or switch between siRNA and miRNA mode, to see how each shifts the balance between cleavage and repression.

⚙ Under the hood

2D схематичний шлях — від поперечного ДНК-РНК до дісера, далі до пари РІСК і гідролізу/загальняння на основі комплементарності.

RNA InterferenceGene SilencingMolecular BiologyBiotechnologyGenetics

2D · HTML5 Canvas 2D · 60 FPS target · runs fully client-side, no install