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Induced-Fit Enzyme Catalysis

Interactive 3D enzyme active-site simulator: watch a bilobed enzyme close around a diffusing substrate (induced fit), form the ES complex, and release product, with live Michaelis-Menten kinetics, competitive inhibition and temperature-dependent denaturation.

Molecular Biology3DModerate60 FPS📱 Mobile-adapted⇄ 2D version

This simulator visualizes the induced-fit model of enzyme catalysis: a bilobed active site that flexes around a diffusing substrate molecule, stabilizes the transition state, and releases product before reopening for the next turnover. Adjust substrate concentration, active-site flexibility, temperature and a competitive inhibitor to watch how each one reshapes the catalytic cycle, and read live Michaelis-Menten kinetics — reaction velocity, apparent Km, cumulative product and a temperature-dependent rate factor that collapses once the enzyme denatures.

⚙ Under the hood

Watch a bilobed enzyme active site flex around a diffusing substrate (induced fit), form the ES complex and release product, with live Michaelis-Menten kinetics, competitive inhibition and temperature-dependent denaturation.

enzyme kineticsinduced fitMichaelis-Mentenbiochemistryactive siteinhibition

3D · Three.js / WebGL renderer · 60 FPS target · runs fully client-side, no install