HomeMolecular BiologyTreg IL-2 Sink 2D: Cytokine Field Map

Treg IL-2 Sink 2D: Cytokine Field Map

Interactive 2D reaction-diffusion simulation of regulatory T cell (Treg) suppression via IL-2 deprivation, rendered as a live cytokine-concentration heatmap on a tissue lattice: watch high-affinity CD25 on Tregs starve effector T cells of IL-2, triggering cytokine-withdrawal apoptosis.

Molecular Biology2DAdvanced60 FPS📱 Mobile-adapted⇄ 3D version
2d-treg-cell-immune-tolerance-suppression ↗ Open standalone

Regulatory T cells (Tregs) don't need to kill effector T cells to shut down an immune response — they can simply starve them. This 2D version solves a real reaction-diffusion equation for interleukin-2 (IL-2) on a flat tissue lattice, lets effector T cells (red) secrete IL-2 when activated and consume it to stay alive, and lets Tregs (blue) act as high-affinity CD25 sinks that out-compete them for the same cytokine pool via saturating Michaelis–Menten kinetics — with the entire concentration field rendered directly as a heatmap instead of a 3D voxel cube. Tune Treg number, CD25 avidity, antigen-driven secretion and tissue diffusion, and watch the field and effector population settle into a new equilibrium, including outright cytokine-withdrawal apoptosis when Tregs win the competition.

⚙ Under the hood

A 2D reaction-diffusion simulation of how regulatory T cells (Tregs) suppress effector T cells by out-competing them for IL-2 through high-affinity CD25 receptors, rendered as a live cytokine-concentration heatmap on a flat tissue lattice instead of a 3D voxel cube — starving effectors into cytokine-withdrawal apoptosis.

immunologyregulatory-t-cellsIL-2reaction-diffusioncell-biologyautoimmunity

2D · HTML5 Canvas 2D · 60 FPS target · runs fully client-side, no install

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