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DNA Replication Environment (2D)

Top-down 2D companion to the 3D DNA replication environment simulator: dial temperature and Mg²⁺ cofactor concentration to see how they set the replisome's fork rate and error rate, then fire a mutagen pulse and watch proofreading either excise the mismatch or let it become a fixed mutation.

Molecular Biology2DEasy60 FPS📱 Mobile-adapted⇄ 3D version

This flat, top-down companion to the 3D DNA replication environment lab isolates the two chemical knobs that actually govern a real replisome: temperature, which sets how fast the polymerase can catalyze bond formation and how close it is to denaturing, and Mg²⁺ concentration, the catalytic cofactor whose excess stabilizes mismatches and blunts the enzyme's own proofreading exonuclease. Moving the sliders continuously recomputes the fork's rate and its live error rate from those two variables, and firing a mutagen pulse injects a mismatched base to test — under whatever conditions are currently dialed in — whether proofreading excises it or it survives as a fixed mutation.

⚙ Under the hood

Top-down 2D companion to the 3D DNA replication environment lab: temperature and Mg²⁺ sliders drive the replisome's live fork rate and error rate, and a mutagen-pulse button tests whether proofreading catches an induced mismatch under the current conditions.

2D · HTML5 Canvas 2D · 60 FPS target · runs fully client-side, no install