Home▸Medical Technology & Imaging Physics▸Biosensor Biofouling & Signal Drift: 2D Diffusion-Path Simulator

Biosensor Biofouling & Signal Drift: 2D Diffusion-Path Simulator

Interactive 2D companion to the 3D biosensor biofouling simulator: watch a fouling protein shell close in around an implanted electrode, track sensitivity decay on a real Fick's-law diffusion-path curve, and compare true versus reported analyte concentration on a live strip chart as recalibration and sensor replacement are put to the test.

Medical Technology & Imaging Physics2DModerate60 FPS📱 Mobile-adapted⇄ 3D version
2d-biotech-topic-12 ↗ Open standalone

An implanted electrochemical biosensor only reports what actually reaches its electrode, and what reaches the electrode changes the moment it is implanted: adsorbed tissue proteins and a maturing fibrous capsule form a biofouling shell that lengthens the diffusion path analyte molecules must cross. This 2D companion to the 3D biosensor simulator keeps the same real Fick's-law diffusion-path model — the fouling layer's thickness follows a saturating growth curve, and sensitivity decays as its inverse — but renders it as a clean top-down cross-section you can pan and zoom, and adds a live true-vs-reported concentration strip chart with no 3D equivalent, so the slow divergence between what the sensor reports and what is actually in the blood is visible as a graph, not just a percentage. A recalibration only zeroes the current offset rather than reversing the underlying drift, and only replacing the sensor resets the fouling clock to zero.

⚙ Under the hood

A 2D top-down companion to the 3D implantable-biosensor biofouling simulator: watch a protein/fibrous-capsule shell close in around an electrode on a real Fick's-law diffusion-path curve, and compare true versus reported analyte concentration on a live strip chart driven by a corrected first-order dosing-pulse model, as recalibration masks drift without reversing it.

biosensorbiofoulingmedtechdiffusiondrug monitoringsignal driftpharmacokinetics

2D · HTML5 Canvas 2D · 60 FPS target · runs fully client-side, no install

What did you find?

Add reproduction steps (optional)