Placental Glucose Transporter (GLUT1) Kinetics Simulator
Interactive 3D model of facilitated glucose transport across the placental syncytiotrophoblast barrier: tune maternal glucose, GLUT1 transporter density and membrane thickness and watch Michaelis-Menten carrier kinetics set fetal glucose delivery in real time.
Glucose is the fetus's principal fuel, and every molecule that reaches it must first cross the syncytiotrophoblast — the single continuous layer of maternal-facing placental cells that separates maternal and fetal blood. This simulator models the real mechanism of that crossing: facilitated diffusion through GLUT1 carrier proteins, following symmetric Michaelis-Menten kinetics rather than simple concentration-driven diffusion. Adjust maternal glucose concentration, GLUT1 transporter density and syncytiotrophoblast thickness and watch net flux, fetal glucose concentration and carrier saturation respond exactly as the underlying transport equation dictates — including the saturation ceiling that keeps fetal glucose delivery from scaling linearly with maternal hyperglycemia.
Interactive 3D model of facilitated glucose transport across the placental syncytiotrophoblast barrier, where GLUT1 carrier proteins follow Michaelis-Menten kinetics to set fetal glucose delivery from maternal blood.
3D · Three.js / WebGL renderer · 60 FPS target · runs fully client-side, no install