Lipid Droplet Ripening & Lipophagy (2D Cross-Section)
2D cross-section simulation of lipid droplet Ostwald ripening: DGAT-driven synthesis, ATGL lipolysis gated by perilipin coverage, and seipin nucleation compete to set droplet count and size, with drag-to-pan and scroll-to-zoom.
This is the 2D cross-section counterpart of the 3D lipid-droplet biogenesis simulator. Droplets still bud from the endoplasmic reticulum as neutral-lipid lenses at seipin-marked sites and still grow and shrink under the same three competing processes — Lifshitz–Slyozov–Wagner Ostwald ripening, DGAT-driven triglyceride synthesis biased by surface area, and ATGL-mediated surface lipolysis that perilipin coating can suppress — but rendered here as a flat, pannable, zoomable cross-section rather than a 3D scene. Adjust synthesis, lipolysis, perilipin coverage and nucleation rate independently, fire a fasting pulse to watch hormone-sensitive lipolysis strip the perilipin coat and shrink the pool, and track live droplet count, total lipid volume, mean radius and net volume flux as the population coarsens.
2D cross-section counterpart of the 3D lipid droplet simulator: droplets bud from the ER and coarsen by Ostwald ripening, with DGAT-driven triglyceride synthesis competing against perilipin-gated ATGL lipolysis. Drag to pan, scroll to zoom.
2D · HTML5 Canvas 2D · 60 FPS target · runs fully client-side, no install