🧬 Antigen Presentation & T-cell Priming: TCR Affinity Simulator (2D)
Interactive 2D kinetic-proofreading model of TCR-pMHC binding affinity. Adjust receptor affinity, costimulation and MHC class to see which T-cells clear the proofreading checkpoints for Signal 1 and become fully activated versus anergic.
⚙ Under the hood
Interactive 2D kinetic-proofreading model of TCR-pMHC binding affinity. Adjust receptor affinity, costimulation and MHC class to see which T-cells clear the proofreading checkpoints for Signal 1 and become fully activated versus anergic.
ImmunologyT-cellMHCBinding AffinityKinetic ProofreadingVaccine Design
2D · HTML5 Canvas 2D · 60 FPS target · runs fully client-side, no install