Home▸Immunology & Vaccine Design▸Antigen Presentation & T-cell Priming: TCR Affinity Simulator (2D)

🧬 Antigen Presentation & T-cell Priming: TCR Affinity Simulator (2D)

Interactive 2D kinetic-proofreading model of TCR-pMHC binding affinity. Adjust receptor affinity, costimulation and MHC class to see which T-cells clear the proofreading checkpoints for Signal 1 and become fully activated versus anergic.

Immunology & Vaccine Design2DAdvanced60 FPS📱 Mobile-adapted⇄ 3D version
2d-antigen-presentation-tcell-priming-simulator ↗ Open standalone
⚙ Under the hood

Interactive 2D kinetic-proofreading model of TCR-pMHC binding affinity. Adjust receptor affinity, costimulation and MHC class to see which T-cells clear the proofreading checkpoints for Signal 1 and become fully activated versus anergic.

ImmunologyT-cellMHCBinding AffinityKinetic ProofreadingVaccine Design

2D · HTML5 Canvas 2D · 60 FPS target · runs fully client-side, no install

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