Home▸Genetics & Evolution▸CRISPR-Cas9 Lab: PAM Scan, Guide Mismatches, R-Loop Zipper and DNA Repair Outcomes

🧬 CRISPR-Cas9 Lab: PAM Scan, Guide Mismatches, R-Loop Zipper and DNA Repair Outcomes

Watch a Cas9 and guide-RNA complex slide along a DNA helix, find a PAM, unzip an R-loop and cut, then see how NHEJ and HDR repair the break. Toggle mismatches to learn why seed positions matter and how off-target cutting is estimated.

Genetics & Evolution3DAdvanced60 FPS📱 Mobile-adapted🟠 Blender

⚙ Under the hood

CRISPRCas9Guide RNADNA RepairOff-target

3D · Three.js / WebGL renderer · 60 FPS target · runs fully client-side, no install