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Stem Cell Transplant Engraftment Simulator

Interactive hematopoietic stem cell transplant simulator: dose donor CD34+ cells, set HLA match, conditioning intensity and immunosuppression, then watch marrow niche engraftment, neutrophil/platelet recovery curves and graft rejection risk play out day by day in real 3D.

Genetics & Evolution2DModerate60 FPS📱 Mobile-adapted

This simulation models a hematopoietic stem cell transplant: donor CD34+ cells are infused, home to marrow niches cleared by the conditioning regimen, and expand through a logistic growth process until the graft saturates the available niche capacity. Set the donor cell dose, HLA match quality, conditioning intensity and post-transplant immunosuppression, then watch the 3D marrow lattice fill with donor-derived cells while live neutrophil (ANC) and platelet recovery curves track toward clinical engraftment thresholds — with a real, match-dependent daily risk of graft rejection built into the model.

⚙ Under the hood

This simulation allows users to explore the complex process of stem cell differentiation and proliferation within a controlled environment, simulating the key stages of advanced therapies.

Stem Cell TherapyCell ProliferationDifferentiation

2D · HTML5 Canvas 2D · 60 FPS target · runs fully client-side, no install