🥜 Oral Immunotherapy (Palforzia) Desensitization Simulator

Day One — Starting From a Microscopic Peanut Protein Dose

Placeholder: therapy begins with tiny, closely monitored doses.

• 0.5 mg: Starting dose (placeholder starting amount)
• ~5 hrs: Clinic duration (placeholder observation time)
• ~10: Dose steps (placeholder step count)
• Highest: Reaction risk (placeholder risk note)

Placeholder heading — initial dose escalation

Placeholder text describing the initial in-clinic dose escalation day.

Up-Dosing — Gradual Increases Toward the Maintenance Target

Placeholder: dose rises in steps roughly every two weeks.

• ~6 mo: Duration (placeholder phase length)
• 11: Dose levels (placeholder level count)
• 300 mg: Target dose (placeholder end target)
• Biweekly: Visit frequency (placeholder cadence)

Placeholder heading — up-dosing schedule

Placeholder text describing the biweekly up-dosing schedule.

Maintenance — Holding a Steady Daily Peanut Protein Dose

Placeholder: a fixed daily dose is continued indefinitely.

• 300 mg: Maintenance dose (placeholder fixed dose)
• Daily: Dosing (placeholder frequency)
• Ongoing: Duration (placeholder duration note)
• High: Compliance need (placeholder adherence note)

Placeholder heading — maintenance phase

Placeholder text describing the maintenance dosing phase.

Reactivity Threshold — How Much Tolerance Is Gained

Placeholder: tolerated allergen amount increases over time.

• ~1000 mg: Threshold gain (placeholder tolerance gain)
• ~2 mg: Baseline threshold (placeholder starting tolerance)
• Food challenge: Measured by (placeholder test method)
• 12–24 mo: Timeframe (placeholder timeline)

Placeholder heading — threshold elevation

Placeholder text describing reactivity threshold elevation over months.

Accidental Exposure — The Practical Safety Benefit

Placeholder: higher threshold reduces risk from hidden traces.

• Substantial: Protection gain (placeholder benefit note)
• Reduced: Severe reaction risk (placeholder risk reduction)
• True: Not a cure (placeholder caveat)
• Required: Ongoing dosing (placeholder requirement)

Placeholder heading — accidental exposure benefit

Placeholder text describing the accidental-exposure protection benefit.

Placeholder highlight: elevated threshold lowers accidental-exposure reaction risk.