👄 Recurrent Canker Sore Nutritional Deficiency Simulator

Vitamin B12 Deficiency and Recurrent Aphthous Stomatitis

Low serum B12 is repeatedly associated with recurrent mouth ulcers.

• ~28%: B12 deficiency in RAS (placeholder cohort estimate)
• 200–900: Normal B12 range (pg/mL placeholder)
• Weeks: Response to correction (placeholder timeframe)
• Diet/absorption: Common source (placeholder cause)

B12 and mucosal healing

Placeholder: B12 supports epithelial turnover and ulcer healing.

Placeholder insight: B12 repletion may reduce outbreak frequency.

Iron Deficiency and Aphthous Ulcer Recurrence

Low ferritin is another commonly cited deficiency in recurrent cases.

• ~20%: Iron deficiency in RAS (placeholder cohort estimate)
• 20–250: Normal ferritin (ng/mL placeholder)
• Common: Anemia overlap (placeholder comorbidity)
• Months: Correction window (placeholder timeframe)

Iron and mucosal integrity

Placeholder: iron supports mucosal barrier and immune function.

Placeholder insight: ferritin repletion may reduce recurrence rate.

Folate Deficiency and Recurrent Canker Sores

Folate deficiency is also linked to aphthous ulcer recurrence.

• ~15%: Folate deficiency in RAS (placeholder cohort estimate)
• >3: Normal folate (ng/mL placeholder)
• Leafy greens: Diet association (placeholder source)
• Frequent: Combined deficiency (placeholder overlap note)

Folate and cell turnover

Placeholder: folate supports rapid epithelial cell replication.

Placeholder insight: folate correction may shorten flare duration.

Laboratory Workup for Suspected Nutritional Deficiency

CBC, B12, ferritin and folate panels identify correctable causes.

• 4 tests: Panel components (placeholder list)
• 1–3 days: Turnaround time (placeholder estimate)
• Recurrent flares: Referral trigger (placeholder criterion)
• Low: Cost tier (placeholder estimate)

When to order the panel

Placeholder: order labs for frequent or severe recurrent ulcers.

Placeholder insight: early workup guides targeted supplementation.

Supplementation and Reduction in Ulcer Recurrence

Correcting deficiency over weeks tends to lower flare frequency.

• 2–4 wks: Response onset (placeholder estimate)
• Up to 60%: Frequency reduction (placeholder estimate)
• 8–12 wks: Full response (placeholder estimate)
• Possible: Relapse if stopped (placeholder note)

Tracking response over time

Placeholder: frequency typically declines as nutrient levels normalize.

Placeholder insight: sustained supplementation supports lasting remission.