🩸 Synthetic Blood: The Real Science Behind Manufactured Oxygen Carriers
An interactive 3D vessel cutaway comparing how red blood cells, hemoglobin-based oxygen carriers and perfluorocarbon emulsions load and release oxygen.
A cutaway blood vessel comparing how native red blood cells, hemoglobin-based oxygen carriers (HBOCs) and perfluorocarbon (PFC) emulsions load oxygen at the lung and release it at the tissue.
🔬 What It Demonstrates
Each carrier follows a different oxygen-binding curve: red cells unload sharply and cooperatively, cell-free HBOCs cling to oxygen too tightly, and inert PFC droplets simply dissolve oxygen in proportion to pressure.
🎮 How to Use
Pick a carrier, set the tissue oxygen tension and flow rate, then toggle the NO-scavenging effect to see why free-hemoglobin substitutes triggered vasoconstriction and stalled in clinical trials.
💡 Did You Know?
Nearly every hemoglobin-based oxygen carrier tested in large human trials was eventually withdrawn after being linked to a higher risk of heart attack — a direct consequence of free hemoglobin scavenging nitric oxide.
An interactive 3D vessel cutaway comparing how red blood cells, hemoglobin-based oxygen carriers and perfluorocarbon emulsions load and release oxygen.
3D · Three.js / WebGL renderer · 60 FPS target · runs fully client-side, no install