📡 Process Analytical Technology (PAT)

Bioreactor Scale-Up Criterion ComparatorNewScale a stirred-tank bioreactor from bench to production volume under a chosen rule… Real-Time Crystallization Control (PAT)NewAn interactive 3D batch-crystallizer where an inline PAT probe reads supersaturation in real… Chemometric Calibration Drift & RecalibrationNewWatch a spectroscopic PAT calibration model drift out of true as the process baseline… Tablet Compaction: Powder Densification & the Heckel EquationNewWatch a powder bed densify into a tablet between two punches in 3D, driven by the real… In-Line Raman Spectroscopy MonitoringNewIn-line Raman spectroscopy for monitoring concentration in real-time. Near-Infrared (NIR) Blend UniformityNewNear-Infrared (NIR) control of powder blend uniformity prior to tabletting. Soft Sensor Bioprocess State EstimationNewA software sensor for assessing the state of a bioprocess using indirect measurements. Automated Feedback Control Loop (PAT)NewAn automated feedback control loop based on Process Analytical Technology (PAT) data for… Digital Twin of Manufacturing LineNewA digital twin of a manufacturing line that predicts deviations in real-time. Machine Vision Tablet Defect DetectionNewMachine vision for detecting tablet defects on a conveyor belt. Multivariate Data Analysis (MVDA) Batch MonitoringNewMultivariate data analysis of a manufacturing batch for early detection of deviations. Model Predictive Control BioreactorNewModel predictive control of a bioreactor based on kinetic process models.