Quantal Release Statistics: 2D Synapse Model
Interactive 2D model of quantal synaptic transmission: fire trials across a fixed set of release sites, watch the binomial vesicle-release histogram build peak by peak, and see live quantal analysis recover the true release-site count N and release probability p from the mean and variance of the trials.
This 2D counterpart strips the neuromuscular junction down to its core statistics: a fixed grid of N release sites, each an independent coin flip with probability p on every trial. Firing a trial genuinely runs N separate Bernoulli draws, sums the released quanta into an end-plate-potential amplitude, and animates the fusing sites and released transmitter live. Run many trials and the running histogram builds the classic multi-peaked quantal distribution in real time — while a live quantal-analysis panel recovers the true N and p purely from the mean and variance of the trials, exactly as del Castillo and Katz first inferred synaptic quantal content from statistics alone.
Fire an action potential at a 3D neuromuscular junction and watch real binomial vesicle release, Ca2+-dependent quantal content, and end-plate potential summation decide whether the muscle fiber fires.
2D · HTML5 Canvas 2D · 60 FPS target · runs fully client-side, no install