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The STOPP/START Criteria: Safeguarding Older Patients Through Medication Review

A cornerstone in geriatric pharmacotherapy, the STOPP and START criteria help healthcare providers ensure safe and effective medication use.

mysimulator teamUpdated June 2026≈ 4 min read▶ Open the simulation

What STOPP/START Criteria Are

STOPP (Screening Tool of Older Persons’ Potentially Inappropriate Medication) and START (Screening Tool to Alert doctors to Right Treatment) are evidence-based tools designed to identify potentially inappropriate medications in older adults. These criteria focus on common health issues among the elderly, such as polypharmacy, cognitive impairment, and renal insufficiency.

Healthcare providers use STOPP/START to assess whether a medication is appropriate for an individual's condition, age-related factors, and comorbidities, thereby reducing the risk of adverse drug events and optimizing treatment outcomes.

How STOPP/START Criteria Work

The criteria are structured into a series of rules that healthcare providers follow to evaluate medications. Each rule is based on clinical evidence and expert consensus, focusing on specific conditions or medication classes that pose risks for older adults.

For example, STOPP includes rules like 'Antipsychotics in the absence of psychosis' or 'Inappropriate use of sedative hypnotics,' while START provides guidance such as 'Use of a single antihypertensive agent when tolerated and effective.'

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Why It Matters

The STOPP/START criteria are crucial in geriatric care because older adults often take multiple medications, increasing the risk of adverse drug interactions and side effects. By systematically reviewing medication regimens using these tools, healthcare providers can identify and address inappropriate prescriptions, leading to safer and more effective treatment.

Implementing STOPP/START also supports evidence-based decision-making, aligns with best practices in geriatric pharmacotherapy, and helps reduce healthcare costs by minimizing unnecessary medications.

Real-World Applications

In practice, the STOPP/START criteria are used during medication reviews for older adults. Healthcare providers document their findings using these tools to justify de-prescribing or adjusting medication regimens based on clinical evidence and patient needs.

For instance, a provider might use STOPP to identify an inappropriate antipsychotic prescription in an elderly patient with cognitive impairment and then work with the patient's family and other healthcare professionals to find safer alternatives.

Frequently asked questions

What are some common medications that STOPP/START might flag as potentially inappropriate?

STOPP/START may flag medications like antipsychotics for non-psychotic conditions, sedative hypnotics in the elderly, and over-the-counter medications with potential side effects or interactions.

How do healthcare providers use STOPP/START criteria to improve patient outcomes?

By systematically reviewing medication regimens using these tools, healthcare providers can identify and address inappropriate prescriptions, leading to safer and more effective treatment, which ultimately improves patient outcomes.

Are the STOPP/START criteria applicable only in geriatric settings?

While primarily developed for older adults, the principles of STOPP/START are also useful in other populations with complex medication regimens or specific health conditions that may benefit from a structured review process.

How can healthcare providers stay updated on changes to the STOPP/START criteria?

Healthcare providers should regularly consult the latest versions of the STOPP and START guidelines, which are periodically updated based on new evidence and clinical consensus. Professional organizations often provide updates and training sessions.

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