What Acute Cholecystitis Is
Acute cholecystitis is an inflammation of the gallbladder that typically results from obstruction of the cystic duct by a gallstone. This condition can lead to severe pain, fever, and other complications if not promptly diagnosed and treated.
The gallbladder is responsible for storing bile produced in the liver, which aids in digestion. When it becomes inflamed, it can cause significant discomfort and potential damage.
Diagnostic Criteria
Murphy's sign is a key clinical finding used to diagnose acute cholecystitis. It involves palpation of the right upper quadrant while the patient takes a deep breath; if pain is elicited, it suggests inflammation.
Leukocytosis, an elevated white blood cell count, often indicates infection or inflammation in the body and can be indicative of cholecystitis.
Imaging Findings
Ultrasonography is a non-invasive imaging technique that provides critical information about the gallbladder. Wall thickening and pericholecystic fluid are common findings in acute cholecystitis, helping to confirm the diagnosis.
These imaging features help differentiate between other biliary tract disorders such as choledocholithiasis or pancreatitis.
Why It Matters
Prompt and accurate diagnosis of acute cholecystitis is essential for effective treatment, which may include antibiotics, fluid resuscitation, and in severe cases, surgical intervention.
Failure to diagnose can lead to complications such as gangrenous or perforated gallbladder, sepsis, and even death.
Frequently asked questions
What is Murphy's sign?
Murphy's sign is a physical examination finding where the patient experiences severe pain when the right upper quadrant of the abdomen is palpated during inspiration.
How does ultrasonography help in diagnosing acute cholecystitis?
Ultrasonography can detect wall thickening and pericholecystic fluid, which are characteristic findings of acute cholecystitis, aiding in the diagnosis without the need for invasive procedures.
What are the common symptoms of acute cholecystitis?
Common symptoms include right upper quadrant pain that may radiate to the back or shoulder, fever, nausea, and vomiting. Jaundice may also be present in some cases.
Can acute cholecystitis be treated without surgery?
In mild cases, acute cholecystitis can sometimes be managed with conservative treatment such as antibiotics, intravenous fluids, and pain management. However, surgical removal of the gallbladder (cholecystectomy) is often necessary in more severe or recurrent cases.
Try it live
Everything above runs in your browser — open Acute Cholecystitis Diagnostic Pathway Simulator and change the parameters while it is running. Nothing is installed, nothing is uploaded, the whole model lives in one tab.
▶ Open Acute Cholecystitis Diagnostic Pathway Simulator simulation