Elements
In-line/at-line spectroscopy
Sensors and chemometrics
Feedback control and models
Example
Example: Real-Time Crystallization Control
Deploy in-line Raman probe.
Model supersaturation.
Control seeding and cooling.
Frequently asked questions
Accuracy?
Calibration and validation.
Integration?
DCS/MES connectivity.
Cost?
ROI via yields and safety.
Data?
Quality and governance.
Models?
Maintain and update.
Regulatory?
ICH Q8–Q10 alignment.
Sampling?
Representativeness.
Scale?
From lab to plant.
Alarms?
Thresholds and actions.
Outlook?
Closed-loop autonomy.
Try it live
Everything above runs in your browser — open Reaction-Diffusion and change the parameters while it is running. Nothing is installed, nothing is uploaded, the whole model lives in one tab.
▶ Open Reaction-Diffusion simulation