Medical Transcriptomics: One Genome, Many Cell Identities
Select a liver cell, neuron, skin cell or muscle cell and watch the same shared DNA strand switch which gene loci open, bind transcription factors and transcribe RNA — cell identity comes from which genes are active, not from different DNA.
Select a liver cell, neuron, skin cell or muscle cell and watch chromatin open, transcription factors dock and RNA stream out at that cell type's characteristic gene loci along a single shared DNA strand — while every other cell type's loci stay dormant on the exact same molecule.
Select a liver cell, neuron, skin cell or muscle cell and watch the same shared DNA strand switch which gene loci open, bind transcription factors and transcribe RNA — cell identity comes from which genes are active, not from different DNA.
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