🧂 Sodium Homeostasis: How the Body Balances Blood Sodium
Explore how aldosterone, atrial natriuretic peptide, and the kidneys work together to keep blood sodium in the roughly 135 to 145 mEq/L range, and what happens when that balance fails.
This simulation demonstrates how aldosterone and atrial natriuretic peptide push renal sodium handling in opposite directions to keep serum sodium and extracellular fluid volume stable.
🔬 What It Demonstrates
This simulation demonstrates how aldosterone and atrial natriuretic peptide push renal sodium handling in opposite directions to keep serum sodium and extracellular fluid volume stable.
🎮 How to Use
Adjust aldosterone and ANP levels to see how distal nephron sodium reabsorption, urine sodium excretion, and extracellular fluid volume respond in real time.
💡 Did You Know?
Did you know the heart doubles as an endocrine organ? Stretched atrial muscle cells release ANP directly into the blood, making the heart itself a volume sensor that helps regulate kidney function.
Explore how aldosterone, atrial natriuretic peptide, and the kidneys work together to keep blood sodium in the roughly 135 to 145 mEq/L range, and what happens when that balance fails.
3D · Three.js / WebGL renderer · 60 FPS target · runs fully client-side, no install