Home▸Medical Technology & Imaging Physics▸The Menstrual Cycle: A 28-Day Hormonal Feedback Loop

🌙 The Menstrual Cycle: A 28-Day Hormonal Feedback Loop

Explore how the hypothalamic-pituitary-ovarian axis drives the menstrual cycle through pulsatile GnRH, rising estrogen, and a rare switch from negative to positive feedback that triggers ovulation.

Medical Technology & Imaging Physics3DModerate60 FPS

This simulator demonstrates how pulsatile GnRH, FSH, LH, estrogen, and progesterone interact across a 28-day cycle, including the pivotal moment when rising estrogen flips the hypothalamic-pituitary feedback from negative to positive.

🔬 What It Demonstrates

🎮 How to Use

Step through or scrub across the cycle day by day to watch each hormone curve rise and fall, and observe how the feedback mode indicator switches from negative to positive right before the LH surge and ovulation.

💡 Did You Know?

Did you know that the same estrogen molecule can either suppress or stimulate the exact same brain cells, purely depending on how high its concentration climbs and how long it stays there?

⚙ Under the hood

Explore how the hypothalamic-pituitary-ovarian axis drives the menstrual cycle through pulsatile GnRH, rising estrogen, and a rare switch from negative to positive feedback that triggers ovulation.

menstrual cyclehormonesendocrinologyfeedback loopreproductive physiologybiology simulationovulationhpo axis

3D · Three.js / WebGL renderer · 60 FPS target · runs fully client-side, no install