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Hypoxic Pulmonary Vasoconstriction Lab (2D)

A 2D schematic of the lung's unique reflex where low alveolar oxygen makes nearby arterioles constrict instead of dilate — tune the ventilation pattern, hypoxic oxygen level and reflex gain and watch blood flow reroute and lung resistance change in real time.

Medical Technology & Imaging Physics2DModerate60 FPS⇄ 3D version
2d-hypoxic-pulmonary-vasoconstriction-lab ↗ Open standalone

This 2D companion drives the same hypoxic-pulmonary-vasoconstriction (HPV) gain formula as the 3D version through a flat schematic: ten alveolar segments across two lobes each feed from a central pulmonary-artery hub through a vessel whose radius and color respond to a real constriction formula, clamp(gain × (100 − O₂) / 100, 0, 0.85). Pick Normal, Regional (a single blocked segment) or Global (whole-lung, high-altitude) hypoxia, drag the hypoxic-O₂ and gain sliders, and watch blood-flow particles reroute toward better-ventilated segments while a Poiseuille-law resistance index (mean 1/r⁴ across all vessels) shows when local redirection turns into a whole-lung pressure load — the same mechanism behind altitude-related pulmonary hypertension.

⚙ Under the hood

2D schematic HPV lab: tune alveolar oxygen, reflex gain and hypoxia pattern across a ten-segment lung and watch arterioles genuinely constrict, blood reroute, and a Poiseuille-based resistance index respond in real time.

physiologyrespiratory systempulmonary circulationhypoxiavascular biologypoiseuille's law

2D · HTML5 Canvas 2D · 60 FPS target · runs fully client-side, no install

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