🧬 Genetic Drift

Small N (fast drift)
Large N (stable)
50/50 start
Weak selection
Generation0
Fixed (p=1)0%
Lost (p=0)0%
Segregating100%
Mean heterozygosity—
Mean time to fix/loss—
Effective N (Ne)—
In the Wright-Fisher model each generation draws N diploid individuals (2N alleles) by binomial sampling from the parent allele pool. With no selection the expected frequency is unchanged, but sampling variance makes p wander until it fixes (p=1) or is lost (p=0). Smaller populations drift faster; heterozygosity 2p(1−p) decays by a factor (1−1/2N) each generation.