Home▸Biology▸Wound Healing Cell Migration Simulator

🩹 Wound Healing Cell Migration Simulator

Interactive 3D tissue-gap model where adjusting growth-factor concentration and cell adhesion shows how a collective migration front closes a wound over time.

Biology3DModerate60 FPS

A 3D tissue-gap model of a scratch-assay wound: two epithelial sheets sense growth-factor cues at the injured margin and migrate collectively, closing the gap as leader cells pull their followers forward.

🔬 What It Demonstrates

Migration speed depends on growth-factor concentration and follows the biphasic adhesion relationship seen in real epithelial sheets: too little adhesion causes disorganised, fingering fronts, too much causes jamming, and speed peaks in between.

🎮 How to Use

Raise growth factor to speed up closure, sweep cell-cell adhesion to see the front go from ragged to jammed to smooth, and set the wound gap width before resetting to watch a fresh injury heal.

💡 Did You Know?

Leader cells at a real wound margin extend actin-rich lamellipodia and drag their neighbours along through cadherin junctions — the same collective-migration mechanism that, when hijacked, drives invasive cancer cell fronts.

⚙ Under the hood

Interactive 3D tissue-gap model where adjusting growth-factor concentration and cell adhesion shows how a collective migration front closes a wound over time.

wound-healingcell-migrationtissue-regenerationbiophysicscollective-cell-behaviourbiology

3D · Three.js / WebGL renderer · 60 FPS target · runs fully client-side, no install