🧪 Potassium Homeostasis: How Aldosterone and the Kidneys Keep Blood Potassium in a Narrow Range
Explore how the body defends serum potassium between 3.5 and 5.0 mEq/L using insulin-driven cellular shifts and aldosterone-regulated renal excretion, and why this tight control is essential for normal heart rhythm.
This simulator demonstrates how insulin-driven cellular uptake and aldosterone-regulated renal excretion work together on different timescales to keep serum potassium within its narrow normal range.
🔬 What It Demonstrates
This simulator demonstrates how insulin-driven cellular uptake and aldosterone-regulated renal excretion work together on different timescales to keep serum potassium within its narrow normal range.
🎮 How to Use
Adjust potassium intake, insulin levels, and aldosterone activity to see how serum potassium responds, and watch how the resting membrane potential and simulated ECG change as levels move toward hypokalemia or hyperkalemia.
💡 Did You Know?
About 98 percent of the body's potassium is stored inside cells, so the small amount circulating in blood, which is what a lab test actually measures, is only a thin and tightly guarded slice of the total supply.
Explore how the body defends serum potassium between 3.5 and 5.0 mEq/L using insulin-driven cellular shifts and aldosterone-regulated renal excretion, and why this tight control is essential for normal heart rhythm.
3D · Three.js / WebGL renderer · 60 FPS target · runs fully client-side, no install