⏳ Aging & Longevity Science

Autophagy Induction (mTOR/AMPK)NewRegulation of autophagy through inhibition of mTOR and activation of AMPK (rapamycin,… Telomere Attrition & Telomerase ActivationNewShortening of telomeres during cell division, effects of telomerase activation. Biological Age ClockNewCalculation of biological age based on DNA methylation (Horvath clock) and proteomic markers. Cellular Senescence & Senolytic ScreeningNewAccumulation of 'zombie cells' (SASP phenotype), screening senolytics for their selective… NAD+ Metabolism & Sirtuin PathwayNewReduction in NAD+ levels with age, impact of precursors (NMN/NR) on sirtuin pathways.