🚽 The Micturition Reflex: How the Brain and Bladder Coordinate Urination
Explore the spinobulbospinal circuit that governs bladder storage and voiding, from stretch receptors and the pelvic nerve to the pontine micturition center, and see how spinal cord injury disrupts voluntary control.
This simulation demonstrates the complete micturition reflex circuit, showing how stretch receptor signals travel via pelvic nerve afferents to the spinal cord and pontine micturition center, how storage-phase sympathetic and pudendal activity keep the bladder closed, and how voluntary disinhibition triggers the coordinated spinobulbospinal reflex that contracts the detrusor while relaxing both sphincters.
🔬 What It Demonstrates
This simulation demonstrates the complete micturition reflex circuit, showing how stretch receptor signals travel via pelvic nerve afferents to the spinal cord and pontine micturition center, how storage-phase sympathetic and pudendal activity keep the bladder closed, and how voluntary disinhibition triggers the coordinated spinobulbospinal reflex that contracts the detrusor while relaxing both sphincters.
🎮 How to Use
Adjust bladder fill volume to see stretch receptor firing rate rise along the pelvic nerve pathway, then toggle cortical inhibition on and off to see how the pontine micturition center responds. Switch between storage and voiding phase views to compare sympathetic versus parasympathetic dominance and sphincter states, and enable the spinal cord injury mode to see how the circuit breaks down and produces detrusor-sphincter dyssynergia.
💡 Did You Know?
The pontine micturition center's coordinating signal typically completes the full storage-to-voiding transition, from disinhibition through detrusor contraction and sphincter relaxation, in well under a minute, and positive feedback from urethral flow receptors helps sustain the contraction until the bladder is fully empty.
Explore the spinobulbospinal circuit that governs bladder storage and voiding, from stretch receptors and the pelvic nerve to the pontine micturition center, and see how spinal cord injury disrupts voluntary control.
3D · Three.js / WebGL renderer · 60 FPS target · runs fully client-side, no install