🧠 Neurodegenerative & CNS Drug Delivery

Alpha-Synuclein PropagationNewPrion-like propagation of pathologic α-synuclein aggregates between neurons, as described in… Focused Ultrasound BBB OpeningNewFocused ultrasound combined with microbubbles for temporary, controlled opening of the… Amyloid-Beta Aggregation KineticsNewThe kinetics of nucleation and growth of amyloid-β fibrils (Alzheimer's disease), including… Intrathecal / Intranasal CNS DeliveryNewAlternative routes of drug delivery to the central nervous system via the glymphatic system:… Neuroinflammation & Microglia ActivationNewThe cascade of microglial activation, release of pro-inflammatory cytokines, neurotoxicity,…