Damage Control Resuscitation

Massive transfusion protocol simulator — balance PRBC : FFP : platelet ratios, permissive hypotension, TXA timing, and crystalloid volume against the trauma "lethal triad."

Live Physiology

Clot Strength

—

Mortality Risk (24h)

—

Core Temp

—

hypothermia <35°C

Arterial pH

—

acidosis <7.20

Ionized Ca²⁺

—

citrate tox. <0.9

Lactate

—

mmol/L

SBP / HR

—

mmHg / bpm

Units Given

—

PRBC : FFP : PLT

Transfusion Ratio1 : 1 : 1

PRBCFFPPlatelets

FFP per PRBC unit1 : 1

Platelets per PRBC unit1 : 1

Crystalloid Volume1000 mL

Permissive Hypotension

target SBP 80–90 vs. normotensive

TXA Timing (CRASH-2)

None

<1h

1–3h

>3h

PROPPR 2015

CRASH-2 2010

Lethal Triad

Circuit Legend

PRBC (packed red cells)

FFP (fresh frozen plasma)

Platelets (apheresis pack)

Crystalloid (isotonic saline/LR)

Clot forming at wound

Active hemorrhage leak