LAST — Lipid Rescue
Local anesthetic systemic toxicity and the intravenous lipid emulsion "lipid sink"
Current Stage
—
—
Free Bupivacaine
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Cardiac Rhythm
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Lipid Bolus
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MAP (mmHg)
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Lipid Emulsion (20%) Given
0 mL/kg
Toxicity Severity
Moderate
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Free bupivacaine (toxic, membrane)
Lipid droplet (Intralipid)
Bupivacaine sequestered in lipid
Cardiac myocyte membrane
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