Splenomegaly in Infectious Mononucleosis
Spleen enlargement is a common early finding in EBV mononucleosis.
- ~50%: Incidence (placeholder figure)
- Week 2–3: Onset (placeholder figure)
- Palpation/US: Detection (placeholder figure)
- ~4 weeks: Resolution (placeholder figure)
Mechanism of enlargement
Lymphocytic infiltration expands spleen volume.
Splenic Rupture Risk During Physical Activity
An enlarged, fragile spleen can rupture under impact.
- <1%: Rupture rate (placeholder figure)
- Weeks 2–4: Peak risk window (placeholder figure)
- Contact sport: Typical trigger (placeholder figure)
- High: Mortality if untreated (placeholder figure)
Why impact matters
Capsule tension rises with size and force.
Avoid contact sports until spleen size normalizes.
Tonsillar Hypertrophy in EBV Infection
Tonsils enlarge from lymphoid hyperplasia during infection.
- ~80%: Incidence (placeholder figure)
- I–IV: Grade range (placeholder figure)
- Week 1–2: Peak swelling (placeholder figure)
- Variable: Airway impact (placeholder figure)
Tissue changes
Reactive lymphoid tissue expands tonsillar volume.
Airway Obstruction Risk From Tonsillar Swelling
Severe hypertrophy may narrow the pharyngeal airway.
- ~1%: Severe cases (placeholder figure)
- Stridor: Warning sign (placeholder figure)
- Steroids/O2: Management (placeholder figure)
- Rare: ICU need (placeholder figure)
Clinical monitoring
Watch for stridor and desaturation signs.
Escalate care promptly if breathing difficulty appears.
Hepatitis and Liver Involvement in EBV Mononucleosis
Mild hepatitis with elevated liver enzymes is common.
- ~80%: ALT/AST rise (placeholder figure)
- ~5%: Jaundice rate (placeholder figure)
- Rare: Severe hepatitis (placeholder figure)
- Weeks: Recovery (placeholder figure)
Enzyme elevation pattern
Transaminases rise transiently then normalize.