Normal Hormone Fluctuation Baseline
Placeholder: a short overview of the normal menstrual hormone cycle.
- ~28d: Cycle length (Placeholder note)
- ~14: Ovulation day (Placeholder note)
- Mid-cycle: Estrogen peak (Placeholder note)
- Mid-luteal: Progesterone peak (Placeholder note)
Normal cyclical hormone rhythm
Placeholder: brief description of the normal hormone rhythm.
Placeholder highlight: this fluctuation is normal and expected.
Luteal Phase Hormone Shift
Placeholder: description of the post-ovulation luteal phase shift.
- ~14d: Luteal length (Placeholder note)
- Sharp: Progesterone rise (Placeholder note)
- Rapid: Late-luteal drop (Placeholder note)
- Normal: Hormone range (Placeholder note)
Luteal phase hormone dynamics
Placeholder: brief note on the luteal phase hormone shift.
Serotonin Receptor Hypersensitivity
Placeholder: description of abnormal serotonin receptor sensitivity in PMDD.
- Elevated: Receptor reactivity (Placeholder note)
- Normal levels: Trigger (Placeholder note)
- Serotonergic: Affected system (Placeholder note)
- Late luteal: Onset (Placeholder note)
Hypersensitive serotonergic response
Placeholder: brief note on receptor hypersensitivity mechanism.
Placeholder highlight: sensitivity, not hormone level, drives PMDD.
Abnormal Mood / Behavior Response
Placeholder: description of resulting mood and behavior symptoms.
- High: Irritability (Placeholder note)
- High: Mood lability (Placeholder note)
- Elevated: Anxiety (Placeholder note)
- Days: Duration (Placeholder note)
Mood and behavior symptom cascade
Placeholder: brief note on downstream mood symptoms.
Symptom Resolution with Menses
Placeholder: description of symptom relief once menses begins.
- Sharp: Hormone drop (Placeholder note)
- Within days: Symptom relief (Placeholder note)
- Day 1: Cycle restart (Placeholder note)
- Next cycle: Recurrence (Placeholder note)
Resolution at menses onset
Placeholder: brief note on symptom resolution timing.
Placeholder highlight: symptoms resolve then recur next cycle.