🧬 Nociceptor Signaling — 3D

Genuine Three.js companion: same sodium-channel pain-pathway math as the 2D original, in real 3D space

Live Readout

Stimulus

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Generator Pot.

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Eff. Threshold

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AP Fired

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Speed

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Phase

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Stimulus & Fiber

Stimulus Intensity55%

Nerve Fiber Type

Local Anesthetic — Nav Blockade

A non-opioid analgesic strategy: blocking voltage-gated Na⁺ channels (e.g. Nav1.7/1.8) raises the firing threshold instead of dulling perception centrally.

Channel Blockade0%

Legend

Mechanical / thermal / chemical stimulus

Stimulus-gated channel (TRPV1 / Piezo2)

Na⁺ ion influx

Voltage-gated Na⁺ channel (Nav1.7/1.8)

Propagating action potential

Tissue Stimulus

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