Plasma
Readouts
Time
0 s
Occupancy
-
Dominant
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Stage
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Clearance risk (opsonization)
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Binding p = 1-exp(-k_on*affinity*(1-0.85*PEG)*dt); a protein with higher affinity displaces a bound weaker one (Vroman effect): albumin first, then fibrinogen, IgG, C3.