This simulation demonstrates how aldosterone and atrial natriuretic peptide push renal sodium handling in opposite directions to keep serum sodium and extracellular fluid volume stable.
Adjust aldosterone and ANP levels to see how distal nephron sodium reabsorption, urine sodium excretion, and extracellular fluid volume respond in real time.
Sliders let you set aldosterone and ANP levels to observe their combined effect on sodium reabsorption, urine output, and serum sodium concentration.
Did you know the heart doubles as an endocrine organ? Stretched atrial muscle cells release ANP directly into the blood, making the heart itself a volume sensor that helps regulate kidney function.
This simulation demonstrates how aldosterone and atrial natriuretic peptide push renal sodium handling in opposite directions to keep serum sodium and extracellular fluid volume stable.
This simulation demonstrates how aldosterone and atrial natriuretic peptide push renal sodium handling in opposite directions to keep serum sodium and extracellular fluid volume stable.
Adjust aldosterone and ANP levels to see how distal nephron sodium reabsorption, urine sodium excretion, and extracellular fluid volume respond in real time.
Did you know the heart doubles as an endocrine organ? Stretched atrial muscle cells release ANP directly into the blood, making the heart itself a volume sensor that helps regulate kidney function.