The interactive 3D simulation visualizes the full RAAS cascade in sequence, from renin release by kidney juxtaglomerular cells through angiotensin I and II formation in the lungs to aldosterone-driven sodium and water retention in the kidney, showing how each step compounds to raise blood pressure over time.
Adjust the starting blood pressure or blood volume slider to simulate hemorrhage, dehydration, or a low-sodium state, then watch each hormone activate in sequence and observe how blood pressure and blood volume recover over a simulated timescale of minutes to days.
Sliders let you set initial blood pressure and sodium/volume status while toggling ACE inhibitor or ARB blockade to see how each RAAS stage and drug target changes the cascade's outcome.
A single pass of blood through the lungs converts most circulating angiotensin I into angiotensin II, meaning the lungs, not just the kidneys, are an essential organ in blood pressure regulation.
The interactive 3D simulation visualizes the full RAAS cascade in sequence, from renin release by kidney juxtaglomerular cells through angiotensin I and II formation in the lungs to aldosterone-driven sodium and water retention in the kidney, showing how each step compounds to raise blood pressure over time.
The interactive 3D simulation visualizes the full RAAS cascade in sequence, from renin release by kidney juxtaglomerular cells through angiotensin I and II formation in the lungs to aldosterone-driven sodium and water retention in the kidney, showing how each step compounds to raise blood pressure over time.
Adjust the starting blood pressure or blood volume slider to simulate hemorrhage, dehydration, or a low-sodium state, then watch each hormone activate in sequence and observe how blood pressure and blood volume recover over a simulated timescale of minutes to days.
A single pass of blood through the lungs converts most circulating angiotensin I into angiotensin II, meaning the lungs, not just the kidneys, are an essential organ in blood pressure regulation.